The small molecule WNT/β-catenin inhibitor CWP232291 blocks the growth of castration-resistant prostate cancer by activating the endoplasmic reticulum stress pathway

BACKGROUND: Androgen receptor (AR)-targeted treatments improve the survival of castration-resistant prostate cancer (CRPC) patients; however, secondary resistance to these agents ultimately occurs in virtually all patients. Therefore, alternative therapeutic targets are urgently needed. Since growin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pak, Sahyun, Park, Sejun, Kim, Yunlim, Park, Jung-Hyuck, Park, Chan-Hee, Lee, Kyoung-June, Kim, Choung-soo, Ahn, Hanjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685284/
https://www.ncbi.nlm.nih.gov/pubmed/31387608
http://dx.doi.org/10.1186/s13046-019-1342-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685284/
https://www.ncbi.nlm.nih.gov/pubmed/31387608
http://dx.doi.org/10.1186/s13046-019-1342-5

Ejemplares similares