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The small molecule WNT/β-catenin inhibitor CWP232291 blocks the growth of castration-resistant prostate cancer by activating the endoplasmic reticulum stress pathway

BACKGROUND: Androgen receptor (AR)-targeted treatments improve the survival of castration-resistant prostate cancer (CRPC) patients; however, secondary resistance to these agents ultimately occurs in virtually all patients. Therefore, alternative therapeutic targets are urgently needed. Since growin...

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Detalles Bibliográficos
Autores principales:	Pak, Sahyun, Park, Sejun, Kim, Yunlim, Park, Jung-Hyuck, Park, Chan-Hee, Lee, Kyoung-June, Kim, Choung-soo, Ahn, Hanjong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685284/ https://www.ncbi.nlm.nih.gov/pubmed/31387608 http://dx.doi.org/10.1186/s13046-019-1342-5

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