Nrf2 Induction Re-establishes a Proper Neuronal Differentiation Program in Friedreich’s Ataxia Neural Stem Cells

Frataxin deficiency is the pathogenic cause of Friedreich’s Ataxia, an autosomal recessive disease characterized by the increase of oxidative stress and production of free radicals in the cell. Although the onset of the pathology occurs in the second decade of life, cognitive differences and defects...

Descripción completa

Detalles Bibliográficos
Autores principales: La Rosa, Piergiorgio, Russo, Marta, D’Amico, Jessica, Petrillo, Sara, Aquilano, Katia, Lettieri-Barbato, Daniele, Turchi, Riccardo, Bertini, Enrico S., Piemonte, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685360/
https://www.ncbi.nlm.nih.gov/pubmed/31417369
http://dx.doi.org/10.3389/fncel.2019.00356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685360/
https://www.ncbi.nlm.nih.gov/pubmed/31417369
http://dx.doi.org/10.3389/fncel.2019.00356

Ejemplares similares