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A unique insert in the genomes of high-risk human papillomaviruses with a predicted dual role in conferring oncogenic risk

The differences between high risk and low risk human papillomaviruses (HR-HPV and LR-HPV, respectively) that contribute to the tumorigenic potential of HR-HPV are not well understood but can be expected to involve the HPV oncoproteins, E6 and E7. We combine genome comparison and machine learning tec...

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Detalles Bibliográficos
Autores principales: Auslander, Noam, Wolf, Yuri I., Shabalina, Svetlana A., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685453/
https://www.ncbi.nlm.nih.gov/pubmed/31448109
http://dx.doi.org/10.12688/f1000research.19590.2