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Immune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response

Few studies were conducted investigating the immunological profiles in gastrointestinal stromal tumors (GIST). Adaptive and innate immune cells are present in the tumor microenvironment, indicating GIST as inflamed tumors. In addition, murine models suggested a potential interaction between immune c...

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Detalles Bibliográficos
Autores principales: Pantaleo, Maria A., Tarantino, Giuseppe, Agostinelli, Claudio, Urbini, Milena, Nannini, Margherita, Saponara, Maristella, Castelli, Chiara, Stacchiotti, Silvia, Fumagalli, Elena, Gatto, Lidia, Santini, Donatella, De Leo, Antonio, Marafioti, Teresa, Akarca, Ayse, Sabattini, Elena, Pession, Andrea, Ardizzoni, Andrea, Indio, Valentina, Astolfi, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685519/
https://www.ncbi.nlm.nih.gov/pubmed/31428517
http://dx.doi.org/10.1080/2162402X.2019.1617588