HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory

HPV16 infections are associated with a variety of cancers and there is compelling evidence that the transforming activity of HPV16 critically depends on the expression of the viral oncoproteins E6 and E7. Therapeutic cancer vaccines capable of generating durable and specific immunity against these H...

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Detalles Bibliográficos
Autores principales: Grunwitz, Christian, Salomon, Nadja, Vascotto, Fulvia, Selmi, Abderaouf, Bukur, Thomas, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685602/
https://www.ncbi.nlm.nih.gov/pubmed/31428528
http://dx.doi.org/10.1080/2162402X.2019.1629259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685602/
https://www.ncbi.nlm.nih.gov/pubmed/31428528
http://dx.doi.org/10.1080/2162402X.2019.1629259

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