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Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2

Vitamin C (ascorbic acid, AA) is a well-known regulator of bone and cartilage metabolism. However, the mechanisms of AA’s action in these tissues are only partly understood. In this study, we confirmed that AA contributes to bone and cartilage metabolism by showing decreased articular cartilage and...

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Detalles Bibliográficos
Autores principales: Lindsey, Richard C., Cheng, Shaohong, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685624/
https://www.ncbi.nlm.nih.gov/pubmed/31390373
http://dx.doi.org/10.1371/journal.pone.0220653