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The presence and impact of reference bias on population genomic studies of prehistoric human populations
Haploid high quality reference genomes are an important resource in genomic research projects. A consequence is that DNA fragments carrying the reference allele will be more likely to map successfully, or receive higher quality scores. This reference bias can have effects on downstream population ge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685638/ https://www.ncbi.nlm.nih.gov/pubmed/31348818 http://dx.doi.org/10.1371/journal.pgen.1008302 |