Mapping the Structural Path for Allosteric Inhibition of a Short-Form ATP Phosphoribosyltransferase by Histidine

[Image: see text] ATP phosphoribosyltransferase (ATPPRT) catalyzes the first step of histidine biosynthesis, being allosterically inhibited by the final product of the pathway. Allosteric inhibition of long-form ATPPRTs by histidine has been extensively studied, but inhibition of short-form ATPPRTs...

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Detalles Bibliográficos
Autores principales: Thomson, Catherine M., Alphey, Magnus S., Fisher, Gemma, da Silva, Rafael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685669/
https://www.ncbi.nlm.nih.gov/pubmed/31251578
http://dx.doi.org/10.1021/acs.biochem.9b00282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685669/
https://www.ncbi.nlm.nih.gov/pubmed/31251578
http://dx.doi.org/10.1021/acs.biochem.9b00282

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