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Mapping the Structural Path for Allosteric Inhibition of a Short-Form ATP Phosphoribosyltransferase by Histidine
[Image: see text] ATP phosphoribosyltransferase (ATPPRT) catalyzes the first step of histidine biosynthesis, being allosterically inhibited by the final product of the pathway. Allosteric inhibition of long-form ATPPRTs by histidine has been extensively studied, but inhibition of short-form ATPPRTs...
Autores principales: | Thomson, Catherine M., Alphey, Magnus S., Fisher, Gemma, da Silva, Rafael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685669/ https://www.ncbi.nlm.nih.gov/pubmed/31251578 http://dx.doi.org/10.1021/acs.biochem.9b00282 |
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