Bcl11b prevents catastrophic autoimmunity by controlling multiple aspects of a regulatory T cell gene expression program

Foxp3 and its protein partners establish a regulatory T (T(reg)) cell transcription profile and promote immunological tolerance. However, molecular features contributing to a T(reg)-specific gene expression program are still incompletely understood. We find that the transcription factor Bcl11b is a...

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Detalles Bibliográficos
Autores principales: Hasan, Syed Nurul, Sharma, Amit, Ghosh, Sayantani, Hong, Sung-Wook, Roy-Chowdhuri, Sinchita, Im, Sin-Hyeog, Kang, Keunsoo, Rudra, Dipayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685721/
https://www.ncbi.nlm.nih.gov/pubmed/31457081
http://dx.doi.org/10.1126/sciadv.aaw0706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685721/
https://www.ncbi.nlm.nih.gov/pubmed/31457081
http://dx.doi.org/10.1126/sciadv.aaw0706

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