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Bcl11b prevents catastrophic autoimmunity by controlling multiple aspects of a regulatory T cell gene expression program
Foxp3 and its protein partners establish a regulatory T (T(reg)) cell transcription profile and promote immunological tolerance. However, molecular features contributing to a T(reg)-specific gene expression program are still incompletely understood. We find that the transcription factor Bcl11b is a...
Autores principales: | Hasan, Syed Nurul, Sharma, Amit, Ghosh, Sayantani, Hong, Sung-Wook, Roy-Chowdhuri, Sinchita, Im, Sin-Hyeog, Kang, Keunsoo, Rudra, Dipayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685721/ https://www.ncbi.nlm.nih.gov/pubmed/31457081 http://dx.doi.org/10.1126/sciadv.aaw0706 |
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