Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity

Mycophenolate mofetil (MMF) is commonly prescribed and has proven advantages over other immunosuppressive drugs. However, frequent gastrointestinal side effects through an unknown mechanism limit its use. We have found that consumption of MMF alters the composition of the gut microbiota, selecting f...

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Detalles Bibliográficos
Autores principales: Taylor, Michael R., Flannigan, Kyle L., Rahim, Hannah, Mohamud, Amina, Lewis, Ian A., Hirota, Simon A., Greenway, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685722/
https://www.ncbi.nlm.nih.gov/pubmed/31457102
http://dx.doi.org/10.1126/sciadv.aax2358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685722/
https://www.ncbi.nlm.nih.gov/pubmed/31457102
http://dx.doi.org/10.1126/sciadv.aax2358

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