Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in riboso...

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Detalles Bibliográficos
Autores principales: Halfon, Yehuda, Matzov, Donna, Eyal, Zohar, Bashan, Anat, Zimmerman, Ella, Kjeldgaard, Jette, Ingmer, Hanne, Yonath, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685948/
https://www.ncbi.nlm.nih.gov/pubmed/31391518
http://dx.doi.org/10.1038/s41598-019-48019-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685948/
https://www.ncbi.nlm.nih.gov/pubmed/31391518
http://dx.doi.org/10.1038/s41598-019-48019-1

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