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Ultra-sensitive digital quantification of proteins and mRNA in single cells

Simultaneous measurement of proteins and mRNA in single cells enables quantitative understanding and modeling of cellular functions. Here, we present an automated microfluidic system for multi-parameter and ultra-sensitive protein/mRNA measurements in single cells. Our technology improves the sensit...

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Detalles Bibliográficos
Autores principales: Lin, Jing, Jordi, Christian, Son, Minjun, Van Phan, Hoang, Drayman, Nir, Abasiyanik, Mustafa Fatih, Vistain, Luke, Tu, Hsiung-Lin, Tay, Savaş
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685952/
https://www.ncbi.nlm.nih.gov/pubmed/31391463
http://dx.doi.org/10.1038/s41467-019-11531-z