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Role of p53 isoforms in the DNA damage response during Drosophila oogenesis

The tumor suppressor p53 is involved in the DNA damage response and induces cell cycle arrest or apoptosis upon DNA damage. Drosophila p53 encodes two isoforms, p53A and p53B, that induce apoptosis in somatic cells. To investigate the roles of Drosophila p53 isoforms in female germline cells, the DN...

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Detalles Bibliográficos
Autores principales: Park, Ji-Hong, Nguyen, Tram Thi Ngoc, Lee, Eun-Mi, Castro-Aceituno, Veronica, Wagle, Ram, Lee, Kwang-Soon, Choi, Juyoung, Song, Young-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685966/
https://www.ncbi.nlm.nih.gov/pubmed/31391501
http://dx.doi.org/10.1038/s41598-019-47913-y