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Bcl11b controls odorant receptor class choice in mice

Each olfactory sensory neuron (OSN) expresses a single odorant receptor (OR) gene from the class I or class II repertoire in mice. The mechanisms that regulate OR class choice in OSNs remain unknown. Here, we show that the transcription factor Bcl11b determines the OR class to be expressed in OSNs....

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Detalles Bibliográficos
Autores principales: Enomoto, Takayuki, Nishida, Hidefumi, Iwata, Tetsuo, Fujita, Akito, Nakayama, Kanako, Kashiwagi, Takahiro, Hatanaka, Yasue, Kondo, Hiro, Kajitani, Rei, Itoh, Takehiko, Ohmoto, Makoto, Matsumoto, Ichiro, Hirota, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685970/
https://www.ncbi.nlm.nih.gov/pubmed/31396576
http://dx.doi.org/10.1038/s42003-019-0536-x