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Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca(2+) flickers

Piezo channels transduce mechanical stimuli into electrical and chemical signals to powerfully influence development, tissue homeostasis, and regeneration. Studies on Piezo1 have largely focused on transduction of “outside-in” mechanical forces, and its response to internal, cell-generated forces re...

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Detalles Bibliográficos
Autores principales: Ellefsen, Kyle L., Holt, Jesse R., Chang, Alice C., Nourse, Jamison L., Arulmoli, Janahan, Mekhdjian, Armen H., Abuwarda, Hamid, Tombola, Francesco, Flanagan, Lisa A., Dunn, Alexander R., Parker, Ian, Pathak, Medha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685976/
https://www.ncbi.nlm.nih.gov/pubmed/31396578
http://dx.doi.org/10.1038/s42003-019-0514-3