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Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca(2+) flickers
Piezo channels transduce mechanical stimuli into electrical and chemical signals to powerfully influence development, tissue homeostasis, and regeneration. Studies on Piezo1 have largely focused on transduction of “outside-in” mechanical forces, and its response to internal, cell-generated forces re...
Autores principales: | Ellefsen, Kyle L., Holt, Jesse R., Chang, Alice C., Nourse, Jamison L., Arulmoli, Janahan, Mekhdjian, Armen H., Abuwarda, Hamid, Tombola, Francesco, Flanagan, Lisa A., Dunn, Alexander R., Parker, Ian, Pathak, Medha M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685976/ https://www.ncbi.nlm.nih.gov/pubmed/31396578 http://dx.doi.org/10.1038/s42003-019-0514-3 |
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