Cargando…

Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF), the prototypic progressive fibrotic interstitial lung disease, is thought to be a consequence of repetitive micro-injuries to an ageing, susceptible alveolar epithelium. Ageing is a risk factor for IPF and incidence has been demonstrated to increase with age. Dec...

Descripción completa

Detalles Bibliográficos
Autores principales: Hill, Charlotte, Li, Juanjuan, Liu, Dian, Conforti, Franco, Brereton, Christopher J., Yao, Liudi, Zhou, Yilu, Alzetani, Aiman, Chee, Serena J., Marshall, Ben G., Fletcher, Sophie V., Hancock, David, Ottensmeier, Christian H., Steele, Andrew J., Downward, Julian, Richeldi, Luca, Lu, Xin, Davies, Donna E., Jones, Mark G., Wang, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685977/
https://www.ncbi.nlm.nih.gov/pubmed/31391462
http://dx.doi.org/10.1038/s41419-019-1820-x