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Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types

Non-oncogene addiction (NOA) genes are essential for supporting the stress-burdened phenotype of tumours and thus vital for their survival. Although NOA genes are acknowledged to be potential drug targets, there has been no large-scale attempt to identify and characterise them as a group across canc...

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Detalles Bibliográficos
Autores principales: Hjaltelin, Jessica Xin, Izarzugaza, Jose M. G., Jensen, Lars Juhl, Russo, Francesco, Westergaard, David, Brunak, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685999/
https://www.ncbi.nlm.nih.gov/pubmed/31396397
http://dx.doi.org/10.1038/s41540-019-0104-5