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Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types
Non-oncogene addiction (NOA) genes are essential for supporting the stress-burdened phenotype of tumours and thus vital for their survival. Although NOA genes are acknowledged to be potential drug targets, there has been no large-scale attempt to identify and characterise them as a group across canc...
Autores principales: | Hjaltelin, Jessica Xin, Izarzugaza, Jose M. G., Jensen, Lars Juhl, Russo, Francesco, Westergaard, David, Brunak, Søren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685999/ https://www.ncbi.nlm.nih.gov/pubmed/31396397 http://dx.doi.org/10.1038/s41540-019-0104-5 |
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