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Early life exposures shape the CD4(+) T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life

Early life environmental exposures drive lasting changes to the function of the immune system and can contribute to disease later in life. One of the ways environmental factors act is through cellular receptors. The aryl hydrocarbon receptor (AHR) is expressed by immune cells and binds numerous xeno...

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Detalles Bibliográficos
Autores principales: Burke, Catherine G., Myers, Jason R., Boule, Lisbeth A., Post, Christina M., Brookes, Paul S., Lawrence, B. Paige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686001/
https://www.ncbi.nlm.nih.gov/pubmed/31391494
http://dx.doi.org/10.1038/s41598-019-47866-2