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Early life exposures shape the CD4(+) T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life
Early life environmental exposures drive lasting changes to the function of the immune system and can contribute to disease later in life. One of the ways environmental factors act is through cellular receptors. The aryl hydrocarbon receptor (AHR) is expressed by immune cells and binds numerous xeno...
Autores principales: | Burke, Catherine G., Myers, Jason R., Boule, Lisbeth A., Post, Christina M., Brookes, Paul S., Lawrence, B. Paige |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686001/ https://www.ncbi.nlm.nih.gov/pubmed/31391494 http://dx.doi.org/10.1038/s41598-019-47866-2 |
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