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High Glucose Environments Interfere with Bone Marrow-Derived Macrophage Inflammatory Mediator Release, the TLR4 Pathway and Glucose Metabolism

Macrophages may be a crucial aspect of diabetic complications associated with the inflammatory response. In this study, we examined how hyperglycaemia, a common aspect of diabetes, modulates bone marrow-derived macrophages (BMDMs) under an inflammatory stimulus. To perform this study, BMDMs from non...

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Detalles Bibliográficos
Autores principales: Ayala, Thais Soprani, Tessaro, Fernando Henrique Galvão, Jannuzzi, Grasielle Pereira, Bella, Leonardo Mendes, Ferreira, Karen Spadari, Martins, Joilson O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686006/
https://www.ncbi.nlm.nih.gov/pubmed/31391499
http://dx.doi.org/10.1038/s41598-019-47836-8