Tpz1(TPP1) prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast

In both mammalian and fission yeast cells, conserved shelterin and CST (CTC1-STN1-TEN1) complexes play critical roles in protection of telomeres and regulation of telomerase, an enzyme required to overcome the end replication problem. However, molecular details that govern proper coordination among...

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Detalles Bibliográficos
Autores principales: Mennie, Amanda K., Moser, Bettina A., Hoyle, Alice, Low, Ross S., Tanaka, Katsunori, Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686008/
https://www.ncbi.nlm.nih.gov/pubmed/31396577
http://dx.doi.org/10.1038/s42003-019-0546-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686008/
https://www.ncbi.nlm.nih.gov/pubmed/31396577
http://dx.doi.org/10.1038/s42003-019-0546-8

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