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Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases

Carboxyl (C)-terminal processing proteases (CTPs) participate in protective and regulatory proteolysis in bacteria. The PDZ domain is central to the activity of CTPs but plays inherently different regulatory roles. For example, the PDZ domain inhibits the activity of the signaling protease CtpB by b...

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Detalles Bibliográficos
Autores principales: Chueh, Chuang-Kai, Som, Nilanjan, Ke, Lu-Chu, Ho, Meng-Ru, Reddy, Manjula, Chang, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686036/
https://www.ncbi.nlm.nih.gov/pubmed/31387902
http://dx.doi.org/10.1128/mBio.01129-19