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Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy

High levels of serum free fatty acids (FFAs) are associated with lipotoxicity and type 2 diabetes. Palmitic acid (PA) is the predominant circulating saturated FFA. PA induces mitochondrial superoxide and hydrogen peroxide (H(2)O (2)) generation in cultured podocytes. To elucidate the role of PA in a...

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Detalles Bibliográficos
Autores principales: Lee, Eugene, Lee, Hyun Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686159/
https://www.ncbi.nlm.nih.gov/pubmed/30132841
http://dx.doi.org/10.1002/jcp.26875