SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes

Human papillomaviruses induce a host of anogenital cancers, as well as oropharyngeal cancer (HPV+OPC); human papillomavirus 16 (HPV16) is causative in around 90% of HPV+OPC cases. Using telomerase reverse transcriptase (TERT) immortalized foreskin keratinocytes (N/Tert-1), we have identified signifi...

Descripción completa

Detalles Bibliográficos
Autores principales: James, Claire D., Prabhakar, Apurva T., Otoa, Raymonde, Evans, Michael R., Wang, Xu, Bristol, Molly L., Zhang, Kun, Li, Renfeng, Morgan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686230/
https://www.ncbi.nlm.nih.gov/pubmed/31391281
http://dx.doi.org/10.1128/mSphere.00448-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686230/
https://www.ncbi.nlm.nih.gov/pubmed/31391281
http://dx.doi.org/10.1128/mSphere.00448-19

Ejemplares similares