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SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes
Human papillomaviruses induce a host of anogenital cancers, as well as oropharyngeal cancer (HPV+OPC); human papillomavirus 16 (HPV16) is causative in around 90% of HPV+OPC cases. Using telomerase reverse transcriptase (TERT) immortalized foreskin keratinocytes (N/Tert-1), we have identified signifi...
Autores principales: | James, Claire D., Prabhakar, Apurva T., Otoa, Raymonde, Evans, Michael R., Wang, Xu, Bristol, Molly L., Zhang, Kun, Li, Renfeng, Morgan, Iain M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686230/ https://www.ncbi.nlm.nih.gov/pubmed/31391281 http://dx.doi.org/10.1128/mSphere.00448-19 |
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