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Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma

BACKGROUND: Many patients diagnosed with oesophageal adenocarcinoma (OAC) present with advanced disease and approximately half present with metastatic disease. Patients with localised disease, who are managed with curative intent, frequently undergo neoadjuvant chemoradiotherapy. Unfortunately, ~ 70...

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Detalles Bibliográficos
Autores principales: Bibby, Becky A. S., Miranda, Cecelia S., Reynolds, John V., Cawthorne, Christopher J., Maher, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686260/
https://www.ncbi.nlm.nih.gov/pubmed/31391080
http://dx.doi.org/10.1186/s12885-019-5996-3