Cargando…

Sox2-Dependent 3D Chromatin Interactomes in Transcription, Neural Stem Cell Proliferation and Neurodevelopmental Diseases

In our article, we asked whether Sox2, a transcription factor important in brain development and disease, is involved in gene regulation through its action on long-range interactions between promoters and distant enhancers. Our findings highlight that Sox2 shapes a genome-wide network of promoter-en...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Chia-Lin, Nicolis, Silvia K, Zhu, Yanfen, Pagin, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686325/
https://www.ncbi.nlm.nih.gov/pubmed/31431802
http://dx.doi.org/10.1177/1179069519868224