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Long non-coding RNA GAS5 inhibits DDP-resistance and tumor progression of epithelial ovarian cancer via GAS5-E2F4-PARP1-MAPK axis

BACKGROUND: Epithelial ovarian cancer (EOC) is the malignant tumor of the female reproductive system with the highest fatality rate. Tolerance of chemotherapeutic drugs like cisplatin (DDP) occurring in very early stage is one of the important factors of the poor prognosis of epithelial ovarian canc...

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Detalles Bibliográficos
Autores principales: Long, Xiaoran, Song, Keqi, Hu, Hao, Tian, Qi, Wang, Wenjing, Dong, Qian, Yin, Xia, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686414/
https://www.ncbi.nlm.nih.gov/pubmed/31391118
http://dx.doi.org/10.1186/s13046-019-1329-2