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Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats

BACKGROUND: The adipose afferent reflex (AAR), a sympatho-excitatory reflex, can promote the elevation of sympathetic nerve activity (SNA) and blood pressure (BP). Inflammation in the paraventricular nucleus (PVN) involves sympathetic abnormality in some cardiovascular diseases such as hypertension....

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Detalles Bibliográficos
Autores principales: Ding, Lei, Kang, Ying, Dai, Hang-Bing, Wang, Fang-Zheng, Zhou, Hong, Gao, Qing, Xiong, Xiao-Qing, Zhang, Feng, Song, Tian-Run, Yuan, Yan, Liu, Ming, Zhu, Guo-Qing, Zhou, Ye-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686415/
https://www.ncbi.nlm.nih.gov/pubmed/31391086
http://dx.doi.org/10.1186/s12967-019-2006-0