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Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats
BACKGROUND: The adipose afferent reflex (AAR), a sympatho-excitatory reflex, can promote the elevation of sympathetic nerve activity (SNA) and blood pressure (BP). Inflammation in the paraventricular nucleus (PVN) involves sympathetic abnormality in some cardiovascular diseases such as hypertension....
Autores principales: | Ding, Lei, Kang, Ying, Dai, Hang-Bing, Wang, Fang-Zheng, Zhou, Hong, Gao, Qing, Xiong, Xiao-Qing, Zhang, Feng, Song, Tian-Run, Yuan, Yan, Liu, Ming, Zhu, Guo-Qing, Zhou, Ye-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686415/ https://www.ncbi.nlm.nih.gov/pubmed/31391086 http://dx.doi.org/10.1186/s12967-019-2006-0 |
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