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Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother: a case report

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a disorder of the microvasculature with hemolytic anemia, thrombocytopenia and acute kidney injury. Nowadays, aHUS is successfully treated with eculizumab, a humanized, chimeric IgG2/4 kappa antibody, which binds human complement C5 and blocks...

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Detalles Bibliográficos
Autores principales: Nagarajah, Subagini, Tepel, Martin, Nielsen, Christian, Assing, Kristian, Palarasah, Yaseelan, Andersen, Lise Lotte Torvin, Lange, Lotte Borg, Bistrup, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686417/
https://www.ncbi.nlm.nih.gov/pubmed/31390992
http://dx.doi.org/10.1186/s12882-019-1469-9