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Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother: a case report
BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a disorder of the microvasculature with hemolytic anemia, thrombocytopenia and acute kidney injury. Nowadays, aHUS is successfully treated with eculizumab, a humanized, chimeric IgG2/4 kappa antibody, which binds human complement C5 and blocks...
Autores principales: | Nagarajah, Subagini, Tepel, Martin, Nielsen, Christian, Assing, Kristian, Palarasah, Yaseelan, Andersen, Lise Lotte Torvin, Lange, Lotte Borg, Bistrup, Claus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686417/ https://www.ncbi.nlm.nih.gov/pubmed/31390992 http://dx.doi.org/10.1186/s12882-019-1469-9 |
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