CD4(+) T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B

BACKGROUND: Immune inhibitory receptors play an important role in chronic infections. However, little is known about their role in hepatitis B virus (HBV) infection. Here, we analyzed the relationship between programmed death-1 (PD-1) and lymphocyte activation gene-3 (LAG-3) expression on CD4(+) T c...

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Detalles Bibliográficos
Autores principales: Dong, Yuejiao, Li, Xuefen, Zhang, Lu, Zhu, Qiaoyun, Chen, Chunlei, Bao, Jiaqi, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686459/
https://www.ncbi.nlm.nih.gov/pubmed/31390978
http://dx.doi.org/10.1186/s12865-019-0309-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686459/
https://www.ncbi.nlm.nih.gov/pubmed/31390978
http://dx.doi.org/10.1186/s12865-019-0309-9

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