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Large-scale expansion and characterization of CD3(+) T-cells in the Quantum(®) Cell Expansion System

BACKGROUND: The rapid evolution of cell-based immunotherapies such as chimeric antigen receptor T-cells for treatment of hematological cancers has precipitated the need for a platform to expand these cells ex vivo in a safe, efficient, and reproducible manner. In the Quantum(®) Cell Expansion System...

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Detalles Bibliográficos
Autores principales: Coeshott, Claire, Vang, Boah, Jones, Mark, Nankervis, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686483/
https://www.ncbi.nlm.nih.gov/pubmed/31391068
http://dx.doi.org/10.1186/s12967-019-2001-5