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A seed-extended algorithm for detecting protein complexes based on density and modularity with topological structure and GO annotations

BACKGROUND: The detection of protein complexes is of great significance for researching mechanisms underlying complex diseases and developing new drugs. Thus, various computational algorithms have been proposed for protein complex detection. However, most of these methods are based on only topologic...

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Detalles Bibliográficos
Autores principales: Wang, Rongquan, Wang, Caixia, Sun, Liyan, Liu, Guixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686515/
https://www.ncbi.nlm.nih.gov/pubmed/31390979
http://dx.doi.org/10.1186/s12864-019-5956-y