Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma

BACKGROUND: Hepatitis B virus (HBV) is the major risk factor for hepatocellular carcinoma (HCC). The molecular mechanisms underlying HBV-associated HCC pathogenesis is still unclear. Genetic alterations in cancer-related genes have been linked to many human cancers. Here, we aimed to explore genetic...

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Detalles Bibliográficos
Autores principales: Huang, Fung-Yu, Wong, Danny Ka-Ho, Tsui, Vivien Wai-Man, Seto, Wai-Kay, Mak, Lung-Yi, Cheung, Tan-To, Lai, Keane K.-Y., Yuen, Man-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686555/
https://www.ncbi.nlm.nih.gov/pubmed/31395065
http://dx.doi.org/10.1186/s12885-019-6002-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686555/
https://www.ncbi.nlm.nih.gov/pubmed/31395065
http://dx.doi.org/10.1186/s12885-019-6002-9

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