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RGD conjugated cell uptake off to on responsive NIR-AZA fluorophores: applications toward intraoperative fluorescence guided surgery

The use of NIR-fluorescence imaging to demarcate tumour boundaries for real-time guidance of their surgical resection has a huge untapped potential. However, fluorescence imaging using molecular fluorophores, even with a targeting biomolecule attached, has a major shortcoming of signal interference...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Daly, Harrison C., Grossi, Marco, Conroy, Emer, Li, Bo, Gallagher, William M., Elmes, Robert, O'Shea, Donal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686729/
https://www.ncbi.nlm.nih.gov/pubmed/31588261
http://dx.doi.org/10.1039/c9sc02197c