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Aquaporin expression in the human and canine intervertebral disc during maturation and degeneration

The intervertebral disc (IVD) is a highly hydrated tissue, the rich proteoglycan matrix imbibes water, enabling the disc to withstand compressive loads. During aging and degeneration increased matrix degradation leads to dehydration and loss of function. Aquaporins (AQP) are a family of transmembran...

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Detalles Bibliográficos
Autores principales: Snuggs, Joseph W., Day, Rebecca E., Bach, Frances C., Conner, Matthew T., Bunning, Rowena A. D., Tryfonidou, Marianna A., Le Maitre, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686802/
https://www.ncbi.nlm.nih.gov/pubmed/31463463
http://dx.doi.org/10.1002/jsp2.1049