Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons

Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during axonal growth and pathfinding. However, in mature neurons, axonal ribosomes are significantly...

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Detalles Bibliográficos
Autores principales: Costa, Rui O., Martins, Helena, Martins, Luís F., Cwetsch, Andrzej W., Mele, Miranda, Pedro, Joana R., Tomé, Diogo, Jeon, Noo Li, Cancedda, Laura, Jaffrey, Samie R., Almeida, Ramiro D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686882/
https://www.ncbi.nlm.nih.gov/pubmed/31340150
http://dx.doi.org/10.1016/j.celrep.2019.06.080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686882/
https://www.ncbi.nlm.nih.gov/pubmed/31340150
http://dx.doi.org/10.1016/j.celrep.2019.06.080

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