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Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons
Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during axonal growth and pathfinding. However, in mature neurons, axonal ribosomes are significantly...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686882/ https://www.ncbi.nlm.nih.gov/pubmed/31340150 http://dx.doi.org/10.1016/j.celrep.2019.06.080 |