Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans

Anthracyclines cause progressive cardiotoxicity whose ultimate severity is individual to the patient. Genetic determinants contributing to this variation are difficult to study using current mouse models. Our objective was to determine whether a spectrum of anthracycline induced cardiac disease can...

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Detalles Bibliográficos
Autores principales: Zeiss, Caroline J., Gatti, Daniel M., Toro-Salazar, Olga, Davis, Crystal, Lutz, Cathleen M., Spinale, Francis, Stearns, Timothy, Furtado, Milena B., Churchill, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686936/
https://www.ncbi.nlm.nih.gov/pubmed/31263061
http://dx.doi.org/10.1534/g3.119.400232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686936/
https://www.ncbi.nlm.nih.gov/pubmed/31263061
http://dx.doi.org/10.1534/g3.119.400232

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