HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis

BACKGROUND: Genome-wide association studies have identified chromosome 14q32 as a locus for coronary artery disease. The disease-associated variants fall in a hitherto uncharacterized gene called HHIPL1 (hedgehog interacting protein-like 1), which encodes a sequence homolog of an antagonist of hedge...

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Detalles Bibliográficos
Autores principales: Aravani, Dimitra, Morris, Gavin E., Jones, Peter D., Tattersall, Helena K., Karamanavi, Elisavet, Kaiser, Michael A., Kostogrys, Renata B., Ghaderi Najafabadi, Maryam, Andrews, Sarah L., Nath, Mintu, Ye, Shu, Stringer, Emma J., Samani, Nilesh J., Webb, Tom R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686954/
https://www.ncbi.nlm.nih.gov/pubmed/31163988
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.041059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686954/
https://www.ncbi.nlm.nih.gov/pubmed/31163988
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.041059

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