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Towards a Scalable Synthesis of 2‐Oxabicyclo[2.2.0]hex‐5‐en‐3‐one Using Flow Photochemistry

Cyclobutene lactones hold great potential as synthetic building blocks, yet their preparation by photochemical rearrangement in batch can often be a bottleneck in synthetic studies. We report the use of flow photochemistry as a tool to enable a higher‐throughput approach to the synthesis of 2‐oxabic...

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Detalles Bibliográficos
Autores principales: Williams, Jason D., Otake, Yuma, Coussanes, Guilhem, Saridakis, Iakovos, Maulide, Nuno, Kappe, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686974/
https://www.ncbi.nlm.nih.gov/pubmed/31423462
http://dx.doi.org/10.1002/cptc.201900017