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The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease

Animal models are important in understanding both the pathogenesis of and immunity to tuberculosis (TB). Unfortunately, we are beginning to understand that no animal model perfectly recapitulates the human TB syndrome, which encompasses numerous different stages. Furthermore, Mycobacterium tuberculo...

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Detalles Bibliográficos
Autores principales: Bucsan, Allison N, Mehra, Smriti, Khader, Shabaana A, Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687098/
https://www.ncbi.nlm.nih.gov/pubmed/31381766
http://dx.doi.org/10.1093/femspd/ftz037