CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition

We previously reported that CD133, as a putative cancer stem cell marker, plays an important role in cell proliferation and invasion in colon cancer. To understand the role of CD133 expression in colon cancer, we evaluated the inhibitory effect of CD133 in colon cancer cells. In this study, we gener...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wanlu, Cho, Mee-Yon, Lee, Suji, Jang, Mirae, Park, Junsoo, Park, Rackhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687161/
https://www.ncbi.nlm.nih.gov/pubmed/31393941
http://dx.doi.org/10.1371/journal.pone.0220860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687161/
https://www.ncbi.nlm.nih.gov/pubmed/31393941
http://dx.doi.org/10.1371/journal.pone.0220860

Ejemplares similares